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Neonatal hypoglycaemia is a condition of low blood sugar or low blood glucose in a baby within hours to days following its birth. It can be a serious complication of birth that can result in neonatal seizures and death. This is why many hospitals routinely check the neonate's blood glucose shortly after birth and especially in cases of diabetic mothers, large infants or difficult births.

Glucose is the primary chemical used in the foetal brain for nutrition. The glucose is normally obtained from the mother in the form of glucose passed through the umbilical cord. In some cases, once the umbilical cord is severed, the infant doesn't have enough glucose to feed the body and brain and the glucose level plummets. There can be low blood sugar levels if there is too much insulin floating around the infant's body, such as what happens when the mother's glucose is too high. If there isn't enough glycogen storage in the body because the baby lacks glycogen stores in the liver, there can be neonatal hypoglycaemia. If the baby is using up too much glucose, there can be a low blood glucose situation. This can happen if there was a difficult delivery requiring extra glucose to get through it.

The actual diagnosis of neonatal hypoglycaemia includes a blood sugar of less than 30 mg/dL if checked within the first day of life or if the blood sugar is less than 45 mg/dL if checked after the first day of life. This is not a rare condition and occurs about one to three times out of a thousand live births. Risk factors for the disease include infant sepsis (blood infection), low thyroid conditions or hypothyroidism, certain inborn errors of metabolism, poor oxygenation after birth, intrauterine growth retardation, a big baby, a mother with a diabetic condition, preterm births, small for gestational age children that have no glycogen stores or an infection of the amniotic sac, called chorioamnionitis.

There are many symptoms that would lead the nurse or doctor to suspect neonatal hypoglycaemia. These include being cyanotic or blue in the skin, low motor tone, grunting, breathing problems, neonatal irritability, nausea or vomiting, listlessness, pale skin, breathing pauses or apneic spells. There can also be a poor suck with poor feeding, difficulty maintaining the temperature, rapid breathing, sweating in the infant, tremors or shaking and seizures. When a baby looks sick, it is time to check a blood sugar to see what is going on.

The major test for neonatal hypoglycaemia is a blood glucose test, which can be done using a blood glucose monitor rather than a large laboratory machine. It is usually confirmed in the laboratory if it is low on the monitor screen. The blood sugar is tested every 1-2 hours until the blood sugar is normalized. If there is any question, blood is taken for inborn errors of metabolism or other metabolic disorders. Urine tests tell if there is sugar in the urine or if there are other abnormalities.

The treatment of neonatal hypoglycaemia includes immediately feeding the infant with glucose water, breast milk or formula. This can bring up the level of blood sugar in minor cases of low blood sugar. A nasogastric tube may need to be used to put in glucose if the infant is not sucking vigorously. Sometimes IV glucose may need to be given to keep the blood glucose at a level that is appropriate for life and for brain nourishment. The treatment may last just one day or up to a full week before the infant can bring up its own glucose.

Medications including diazoxide can bring up blood glucose levels in difficult patients and a medication known as ocreotide will lessen the level of insulin produced by the pancreas. In rare cases, an infant cannot lower his or her insulin level and will need a surgery to remove a portion of the pancreas. Sometimes the neonatal hypoglycaemia can be treated once, only to come back in a day or a few hours. This is why careful screening of the glucose level, even after treatment, is warranted.

Once treated, most infants do well after their bout of neonatal hypoglycaemia. If it is not treated adequately or long enough, there can be permanent developmental delay, heart failure, seizure disorder or mental delay.

HELPLINE: ☎ 1800 633 634

Medical Negligence Solicitors

If Neonatal Hypoglycaemia was worsened or was not diagnosed due to mistakes by a doctor or hospital, it is important that you protect your interests and make certain that you are compensated for injury to yourself or your child. Our medical negligence solicitors normally deal with claims using a no win no fee arrangement which means that if you don't win then you don�t pay them their professional costs. If you would like legal advice at no cost then just complete the contact form or email our offices or call the helpline and a Neonatal Hypoglycaemia solicitor will telephone to discuss your potential claim.